Comparison of Central Corneal Thickness Measured through Pentacam, OCTCasia2, and Orbscan IIz in Normal Individuals

Purpose: To compare the central corneal thickness measured through Pentacam, OCTCasia2, and Orbscan IIz in normal individuals. Methods: In this cross sectional comparative study, the researcher investigated the eyes of 70 normal candidates (140 eyes) with the mean age of 31.42 ± 7.70, referring to Dr. Sedaghat eye clinic for refractive surgery. For each person, Central Corneal Thickness (CCT) was measured, using 3 devices including Pentacam, OCTCasia2 and Orbscan. The data were collected and analyzed. The Pearson Correlation Coefficient was employed to assess correlation of 3 devices with each other. Bland-Altman plot was also used to evaluate the agreement between devices. Results: The mean CCT measured through Orbscan, Pentacam, and OCTCasia2 was reported to be 535.06±35.11 µm, 525.21±31.60 µm, and 511.06±30.87 µm, respectively. The Pearson Correlation Coefficient between Pentacam-OCTCasia2, OCTCasia2-Orbscan, Pentacam-Orbscan were r=0.955; P<0.001, r=0.913; P<0.001, r=0.941; P<0.001, respectively. Conclusion: There was a very good correlation and agreement between devices, but none of the devices had the ability to replace each other.